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Creatine monohydrate
Guanidinoacetate methyltransferase (GAMT) deficiency.
Arginine:glycine amidinotransferase (AGAT) deficiency
Creatine transporter defect.
300 - 400 mg/kg/day up to 2 g/kg /day in three to six divided doses (49).
Tablet
Powder
PO
Dehydration, gastrointestinal distress, diarrhea, muscle cramping, renal dysfunction, weight gain, water retention.
4
49. McCrindle BW, O'Neill MB, Cullen-Dean G, Helden E. Acceptability and compliance with two forms of cholestyramine in the treatment of hypercholesterolemia in children: a randomized, crossover trial. J Pediatr 1997;130(2):266-73