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Dextromethorphan
Non-Ketotic Hyperglycinemia
5 - 35 mg/kg/day in 4 divided doses. Blood concentration can be monitored; the therapeutic level is not defined, but should be greater than zero (0) and lower than 100 nmol/L (55-59).
PO
Dizziness, Somnolence, fatigue
4
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57. Gahl WA, Thoene JG, Schneider JA. Cystinosis. N Engl J Med 2002;347(2):111-21 doi: 10.1056/NEJMra020552[published Online First: Epub Date]|.
58. Kleta R, Gahl WA. Pharmacological treatment of nephropathic cystinosis with cysteamine. Expert opinion on pharmacotherapy 2004;5(11):2255-62 doi: 10.1517/14656566.5.11.2255[published Online First: Epub Date]|.
59. Kaiser-Kupfer MI, Gazzo MA, Datiles MB, Caruso RC, Kuehl EM, Gahl WA. A randomized placebo-controlled trial of cysteamine eye drops in nephropathic cystinosis. Archives of ophthalmology 1990;108(5):689-93