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5 to 15 mg/kg/day in 3 divided doses. The dose should be adjusted to achieve adequate control of both fasting hypoglycemia and protein-induced hypoglycemia (61, 62).

50 mg capsules  oral Suspension (5 – 340 mg/mL)

PO

Cardiovascular: Hypotension (7% )

Endocrine metabolic: Hyperglycemia

Gastrointestinal: Nausea and vomiting (4%)

Neurologic: Asthenia, Dizziness (2% )

4

61. Alemzadeh R, Gammeltoft K, Matteson K. Efficacy of low-dose dextromethorphan in the treatment of nonketotic hyperglycinemia. Pediatrics 1996;97(6 Pt 1):924-6

62. Atay E, Bozaykut A, Sezer G. Four cases of neonatal non-ketotic hyperglycinaemia. Annals of tropical paediatrics 2004;24(4):345-7 doi: 10.1179/027249304225019172[published Online First: Epub Date]|.