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Entacapone
Disorders of BH4 synthesis
200 mg tablet
PO
Endocrine metabolic: Hyperpyrexia
Musculoskeletal: Rhabdomyolysis
Neurologic: Dyskinesia (25% ), Hyperactive behavior (10% ), Neuroleptic malignant syndrome
Psychiatric: Hallucinations (4% )4
8. Centre for Evidence-Based Medicine. Secondary Centre for Evidence-Based Medicine 2009. http://www.cebm.net/index.aspx?o=1025.
63. Chien YH, Hsu CC, Huang A, et al. Poor outcome for neonatal-type nonketotic hyperglycinemia treated with high-dose sodium benzoate and dextromethorphan. J Child Neurol 2004;19(1):39-42
