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1.2 grams daily, usually in 2 divided doses; range: 0.9 - 1.5 grams daily (78, 79).

PO

Abdominal pain (9.8% ), Acute appendicitis (1.2% ), Indigestion (19.6%).

1b

78. Borzutzky A, Crompton B, Bergmann AK, et al. Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter. Clin Immunol 2009;133(3):287-94 doi: S1521-6616(09)00767-0 [pii]

10.1016/j.clim.2009.08.006[published Online First: Epub Date]|.

79. Gospe SM, Jr. Neonatal vitamin-responsive epileptic encephalopathies. Chang Gung medical journal 2010;33(1):1-12