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Laronidase (Aldurazyme®)
Mucopolysaccharidosis type 1
100 U/kg/week (98).
2.9 mg/ 5 mL solution for injection
IV
Flushing, injection site reaction (18% ), Rash (36%), antibody development (91% ), complication of infusion (32% headache, upper respiratory infection (32%) and fever.
1b
98. Baldellou A, Andria G, Campbell PE, et al. Paediatric non-neuronopathic Gaucher disease: recommendations for treatment and monitoring. Eur J Pediatr 2004;163(2):67-75 doi: 10.1007/s00431-003-1363-z[published Online First: Epub Date]|.
