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Pyridoxal phosphate (PLP)

Pyridoxal phosphate-dependent seizures.

30 mg/kg/day divided in three or four doses enterally, for three to five days.

30- 50 mg/kg/day divided in 4-6 doses (73, 153).

50 mg tablet

NGT or PO

Acne, skin reactions, allergic reactions, photosensitivity, nausea, vomiting, abdominal pain, loss of appetite, increased liver function test results, paresthesia, somnolence, nausea and headaches.

4

73. Schiff M, Benoist JF, Tilea B, Royer N, Giraudier S, Ogier de Baulny H. Isolated remethylation disorders: do our treatments benefit patients? J Inherit Metab Dis 2011;34(1):137-45 doi: 10.1007/s10545-010-9120-8[published Online First: Epub Date]|.

153. Product information for Polycitra(R), tricitrates oral solution. Secondary Product information for Polycitra(R), tricitrates oral solution. http://www.paipharma.com/pdfs/9a12bf3d-bf1c-4b0f-b39d-2455d7efc124_insert.pdf.

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