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Ammonium tetrathiomolybdate (Coprexa®)

Neurological presentation of Wilson disease

120 mg/day as: 20 mg three times daily with meals and 20 mg 3 times daily between meals for 2 weeks, and then 60 mg/day as:

10 mg three times daily with meals and 10 mg three times daily between meals (20, 21)

20 mg capsules

PO

Nausea and cytopenia

1b

20. Torres RJ, Prior C, Puig JG. Efficacy and safety of allopurinol in patients with hypoxanthine-guanine phosphoribosyltransferase deficiency. Metabolism 2007;56(9):1179-86 doi: S0026-0495(07)00150-3 [pii] 10.1016/j.metabol.2007.04.013[published Online First: Epub Date]|.

21. Cameron JS, Moro F, Simmonds HA. Gout, uric acid and purine metabolism in paediatric nephrology. Pediatr Nephrol 1993;7(1):105-18

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