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Sodium bicarbonate
Persistent metabolic acidosis
Adults: HCO3-(mEq) = 0.2 x weight (kg) x base deficit (mEq/L) or HCO3-(mEq) = 0.5 x weight (kg) x [24 - serum HCO3-(mEq/L)].
Infants and Children: HCO3-(mEq) = 0.3 x weight (kg) x base deficit (mEq/L) or HCO3-(mEq) = 0.5 x weight (kg) x [24 - serum HCO3-(mEq/L)].
If acid-base status is not available: Dose for older Children and Adults: 2-5 mEq/kg I.V. infusion over 4-8 hours; subsequent doses should be based on patient's acid-base status (165).
0.5 mEq/mL solution or dilute the 1 mEq/mL solution 1:1 with sterile water.
IV
Metabolic alkalosis
5
165. Scholte HR, Busch HF, Bakker HD, Bogaard JM, Luyt-Houwen IE, Kuyt LP. Riboflavin-responsive complex I deficiency. Biochimica et biophysica acta 1995;1271(1):75-83